A-PRF / I-PRF plasma treatments

PRF plasma contains a high concentration of fibrin, growth factors that promote cell proliferation, chemotaxis and differentiation, essential processes in osteogenesis (generation of new bone).

Plasma treatments in dentistry

One of the newest techniques successfully used in dentistry, especially in oral implantology and facial aesthetics is the A-PRF and I-PRF technique. A-PRF is a fibrin-rich plasma that is obtained from blood extracted from the patient and processed by specific laboratory procedures, namely centrifugation. Plasma extraction and processing is performed during dental surgery (extraction, sinus lift, dental implant) and these operations are completed with the use of the plasma obtained in the surgical area.


tratamente cu plasm astomatologie A-PRF I-PRF Cluj

PRF plasma contains a high concentration of fibrin, growth factors that promote cell proliferation, chemotaxis and differentiation, essential processes in osteogenesis (generation of new bone).
Centrifugation without anticoagulants allows the recovery of the fibrin clot containing the platelets and therefore their growth factors which are among others, PDGF (Platelet-derived growth factor), TGF Beta (Transforming growth factor beta) and VEGF (Vascular endothelial growth factor). Fibrin thus plays a dual role: cytokine reservoir and cellular healing matrix.

Pre-care instructions and relative contraindications:

This treatment depends very much on the patient's hydration level (patients should start the hydration process 72 hours before treatment). Patients who smoke may have a lower response to this treatment.

Treatment description:

  • A numbing cream is applied to the treatment area
  • Remove approximately 10 cmc of blood from the arm
  • The harvested blood is centrifuged to separate the component cells
  • Platelets, leukocytes and mesenchymal stem cells are separated and used for this procedure
  • The liquid is then transferred into a syringe and injected using a small needle.


  • What is platelet-rich plasma (PRF plasma treatment)?
  • How does PRF plasma treatment work?
  • How much does a PRP / PRF treatment cost?
What is platelet-rich plasma (PRF plasma treatment)?
Platelet-rich plasma or platelet-rich fibrin, also called 'liquid gold', is the perfect solution for stimulating cell growth in the body. Patient blood is extracted, processed in a centrifuge and then used in certain aesthetic treatments to enhance and optimise results. The amazing benefits of A-PRF / i-PRF can be used to stimulate hair growth, diminish the appearance of scars, encourage collagen production in the body and more.
How does PRF plasma treatment work?

Plasma is a component of blood that contains proteins that help blood to clot as well as support cell growth. Platelets are found in the blood and are responsible for recognising and repairing damaged cells by forming a plug or clot. PRF treatments use processes to heal the body rapidly.

Process: a member of the Dentosan Med team will draw your blood using a small needle. The small vial of blood will be placed and spun in a centrifuge to separate the red blood cells from the plasma. The process concentrates the platelet count to about 4x the normal amount. The platelet-rich plasma is then applied locally.  PRF has been shown to help heal the site of dental surgery much faster.

How much does a PRP / PRF treatment cost?
The cost of PRF treatment will vary depending on the area treated. Please see our rates page for more information.

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Dental clinic in Cluj-Napoca, established in 2003 by Dr. Anton Balog and Dr. Cristiana Balog. The clinic offers complete dental treatments at the highest standards.

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